Falcarindiol

Falcarindiol is a polyyne found in carrot roots which has antifungal activity.^[1][2] Falcarindiol is the main compound responsible for bitterness in carrots.^[3] Falcarindiol and other falcarindiol-type polyacetylenes are also found in many other plants of the family Apiaceae, including some commonly used seasonings such as dill and parsley.^[4]

Falcarindiol

Names
Preferred IUPAC name (3R,8S,9Z)-Heptadeca-1,9-diene-4,6-diyne-3,8-diol
Other names cis-Heptadeca-1,9-diene-4,6-diyne-3,8-diol
Identifiers
CAS Number	55297-87-5 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL69018
ChemSpider	4444588
PubChem CID	5281148
CompTox Dashboard (EPA)	DTXSID701030449
InChI InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10-/t16-,17+/m1/s1 Key: QWCNQXNAFCBLLV-YWALDVPYSA-N InChI=1/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10-/t16-,17+/m1/s1 Key: QWCNQXNAFCBLLV-YWALDVPYBU
SMILES CCCCCCC/C=C\[C@H](O)C#CC#C[C@H](O)C=C
Properties
Chemical formula	C17H24O2
Molar mass	260.377 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

A variety of bioactivities have been reported for falcaridiol and the falcarindiol-type polyacetylenes,^[5][6][7] and because of potential health-promoting metabolic effects these compounds are studied as potential nutraceuticals.^[8] Falcarindiol is the most-active among several polyynes found in Devil's club (Oplopanax horridus) that inhibit cell proliferation.^[9]

See also

• Falcarinol