Benexate

Benexate (BEX) is an anti-ulcer agent used in the treatment of acid-related disorders. It is unique in its inability to form salts that are both non-bitter and soluble.^[1][2]

Benexate

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name Phenylmethyl 2-[4-[(diaminomethylideneamino)methyl]cyclohexanecarbonyl]oxybenzoate
CAS Number	78718-52-2
PubChem CID	2316
ChemSpider	2226 Y
UNII	O3PR2X907M
ChEMBL	ChEMBLCHEMBL2104696
Chemical and physical data
Formula	C23H27N3O4
Molar mass	409.486 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(OCc1ccccc1)c3ccccc3OC(=O)C2CCC(C/N=C(\N)N)CC2
InChI InChI=1S/C23H27N3O4/c24-23(25)26-14-16-10-12-18(13-11-16)21(27)30-20-9-5-4-8-19(20)22(28)29-15-17-6-2-1-3-7-17/h1-9,16,18H,10-15H2,(H4,24,25,26) Y Key:IAXUQWSLRKIRFR-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Medical uses

Benexate is approved from treatment of gastric ulcer in Japan.^[3]

Mechanism of action

The mechanism of action of benexate involves promotion of prostaglandin synthesis, protein secretion, and blood flow stimulation in the gastrointestinal tract.^[4]

See also

• Famotidine
• Powder diffraction
• Sugar substitute
• Crystal engineering