Paeoniflorin

Paeoniflorin is a chemical compound which is one of the major constituents of an herbal medicine derived from Paeonia lactiflora.^[1] It can also be isolated from the fresh water fern Salvinia molesta.^[2]

Paeoniflorin

Names
Other names Paeonia moutan Paeony root Peoniflorin
Identifiers
CAS Number	23180-57-6 Y
3D model (JSmol)	Interactive image
ChemSpider	390957
ECHA InfoCard	100.041.327
PubChem CID	442534
UNII	21AIQ4EV64 Y
CompTox Dashboard (EPA)	DTXSID2042648
InChI InChI=1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1 Key: YKRGDOXKVOZESV-WRJNSLSBSA-N InChI=1/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1 Key: YKRGDOXKVOZESV-WRJNSLSBBV
SMILES O=C(OC[C@@]35[C@@H]4[C@]1(O)O[C@H]5O[C@@](C1)([C@@]3(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C4)C)c6ccccc6
Properties
Chemical formula	C23H28O11
Molar mass	480.466 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

In Paeonia, it can form new compounds with addition of phenolic substituents.^[3] In a study in female rats, paeoniflorin was found to inhibit the production of testosterone within the ovaries, however does not significantly affect the production of estradiol.^[4] In mice, paeoniflorin was shown to protect against neuroinflammation and depression-like behavior induced by FN alpha.^[5]