Phenacemide

Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class.^[1] It is a congener and ring-opened analogue of phenytoin (a hydantoin),^[2][3] and is structurally related to the barbiturates and to other hydantoins.^[4] Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity.^[2][3]

Phenacemide

Clinical data
Trade names	Phenurone
AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	N03AX07 (WHO)
Pharmacokinetic data
Elimination half-life	22–25 hours
Identifiers
IUPAC name N-Carbamoyl-2-phenyl-acetamide
CAS Number	63-98-9 Y
PubChem CID	4753
IUPHAR/BPS	7265
DrugBank	DB01121 Y
ChemSpider	4589 Y
UNII	PAI7J52V09
KEGG	D00504 Y
ChEMBL	ChEMBL918 Y
CompTox Dashboard (EPA)	DTXSID6023442
ECHA InfoCard	100.000.519
Chemical and physical data
Formula	C9H10N2O2
Molar mass	178.191 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(NC(=O)N)Cc1ccccc1
InChI InChI=1S/C9H10N2O2/c10-9(13)11-8(12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,10,11,12,13) Y Key:XPFRXWCVYUEORT-UHFFFAOYSA-N Y
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See also

• Pheneturide