CA10

For the U.S. federal circuit court of appeals, see United States Court of Appeals for the Tenth Circuit. For the highway, see California State Route 10. For the congressional district, see California's 10th congressional district.

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.^[5][6][7]

CA10
Identifiers
Aliases	CA10, CA-RPX, CARPX, HUCEP-15, carbonic anhydrase 10
External IDs	OMIM: 604642; MGI: 1919855; HomoloGene: 23201; GeneCards: CA10; OMA:CA10 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.33-q22 Start 51,630,313 bp[1] End 52,160,017 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 92,988,854 bp[2] End 93,492,575 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum cerebellar vermis middle temporal gyrus prefrontal cortex dorsolateral prefrontal cortex pons right frontal lobe Brodmann area 23 Top expressed in lobe of cerebellum cerebellar vermis primary motor cortex habenula ventromedial nucleus anterior amygdaloid area Epithelium of choroid plexus cingulate gyrus prefrontal cortex piriform cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function molecular function carbonate dehydratase activity zinc ion binding carbonic anhydrase Cellular component cellular component Biological process brain development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56934 72605 Ensembl ENSG00000154975 ENSMUSG00000056158 UniProt Q9NS85 P61215 RefSeq (mRNA) NM_001082533 NM_001082534 NM_020178 NM_028296 NM_001361707 NM_001361708 RefSeq (protein) NP_001076002 NP_001076003 NP_064563 NP_082572 NP_001348636 NP_001348637 Location (UCSC) Chr 17: 51.63 – 52.16 Mb Chr 11: 92.99 – 93.49 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.^[7]