Carbonic anhydrase 13

Carbonic anhydrase 13 is a protein that in humans is encoded by the CA13 gene.^[5]

CA13
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3CZV, 3D0N, 3DA2, 4HU1, 4KNM, 4KNN, 4QIZ, 4QJP, 4QJX, 4QSJ
Identifiers
Aliases	CA13, CAXIII, carbonic anhydrase 13
External IDs	OMIM: 611436; MGI: 1931322; HomoloGene: 75207; GeneCards: CA13; OMA:CA13 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q21.2 Start 85,220,587 bp[1] End 85,284,073 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 A1 Start 14,706,787 bp[2] End 14,728,062 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in jejunal mucosa palpebral conjunctiva pancreatic epithelial cell mucosa of ileum nasal epithelium amniotic fluid endothelial cell gingival epithelium skin of arm duodenum Top expressed in meninges esophagus membranous bone lip jejunum mandible vestibular sensory epithelium vestibular membrane of cochlear duct gastric mucosa epithelium of stomach More reference expression data BioGPS n/a
Gene ontology Molecular function zinc ion binding lyase activity metal ion binding carbonate dehydratase activity carbonic anhydrase Cellular component myelin sheath cytosol intracellular membrane-bounded organelle Biological process bicarbonate transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 377677 71934 Ensembl ENSG00000185015 ENSMUSG00000027555 UniProt Q8N1Q1 Q9D6N1 RefSeq (mRNA) NM_198584 NM_024495 RefSeq (protein) NP_940986 NP_078771 Location (UCSC) Chr 8: 85.22 – 85.28 Mb Chr 3: 14.71 – 14.73 Mb PubMed search [3] [4]
Wikidata
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Function

Carbonic anhydrases (CAs) are a family of zinc metalloenzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).^[6][7]