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CBLC

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

CBLC
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Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene.[5][6][7]

Quick facts Available structures, PDB ...

CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling (Keane et al., 1999).[supplied by OMIM][7]

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Interactions

CBLC has been shown to interact with FYN[8] and Epidermal growth factor receptor.[6][9]

References

Further reading

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