Glutamyl aminopeptidase

Glutamyl aminopeptidase (EC 3.4.11.7, aminopeptidase A, aspartate aminopeptidase, angiotensinase A, glutamyl peptidase, Ca²⁺-activated glutamate aminopeptidase, membrane aminopeptidase II, antigen BP-1/6C3 of mouse B lymphocytes, L-aspartate aminopeptidase, angiotensinase A2) is an enzyme encoded by the ENPEP gene. Glutamyl aminopeptidase has also recently been designated CD249 (cluster of differentiation 249).

glutamyl aminopeptidase (aminopeptidase A)
Identifiers
Symbol	ENPEP
Alt. symbols	gp160, CD249
NCBI gene	2028
HGNC	3355
OMIM	138297
RefSeq	NM_001977
UniProt	Q07075
Other data
EC number	3.4.11.7
Locus	Chr. 4 q25
Search for Structures Swiss-model Domains InterPro

Glutamyl aminopeptidase is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. The enzyme degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.^[1]