Indium (111In) capromab pendetide

Indium (¹¹¹In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer.^[1] Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA.^[2] Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single-photon emission computed tomography (SPECT).^[1]

Indium (¹¹¹In) capromab pendetide

Monoclonal antibody
Type	Whole antibody
Source	Mouse
Target	Glutamate carboxypeptidase II
Clinical data
Trade names	Prostascint
ATC code	V09IB04 (WHO)
Identifiers
CAS Number	151763-64-3 N (capromab) 148805-91-8 (pendetide)
ChemSpider	none
UNII	03MZ53X1YS
ChEMBL	ChEMBL1201579 N
NY (what is this?)  (verify)

Early trials with yttrium (⁹⁰Y) capromab pendetide were also conducted.^[3]