Cholestenol Delta-isomerase

In enzymology, a cholestenol Δ-isomerase (EC 5.3.3.5) is an enzyme that catalyzes the chemical reaction

5alpha-cholest-7-en-3beta-ol ${\displaystyle \rightleftharpoons }$ 5alpha-cholest-8-en-3beta-ol

Cholestenol Δ-isomerase
Identifiers
EC no.	5.3.3.5
CAS no.	37318-47-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Hence, this enzyme has one substrate, 5alpha-cholest-7-en-3beta-ol, and one product, 5alpha-cholest-8-en-3beta-ol.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is Delta7-cholestenol Delta7-Delta8-isomerase. This enzyme participates in biosynthesis of steroids.

See also

• Emopamil binding protein