Corticosteroid side-chain-isomerase

In enzymology, a corticosteroid side-chain-isomerase (EC 5.3.1.21) is an enzyme that catalyzes the chemical reaction

11-deoxycorticosterone ${\displaystyle \rightleftharpoons }$ 20-hydroxy-3-oxopregn-4-en-21-al

corticosteroid side-chain-isomerase
Identifiers
EC no.	5.3.1.21
CAS no.	75139-73-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Hence, this enzyme has one substrate, 11-deoxycorticosterone, and one product, 20-hydroxy-3-oxopregn-4-en-21-al.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is 11-deoxycorticosterone aldose-ketose-isomerase.