Cysteine-conjugate transaminase

In enzymology, a cysteine-conjugate transaminase (EC 2.6.1.75) is an enzyme that catalyzes the chemical reaction

S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ S-(4-bromophenyl)mercaptopyruvate + L-glutamate

cysteine-conjugate transaminase
Identifiers
EC no.	2.6.1.75
CAS no.	117698-05-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are S-(4-bromophenyl)-L-cysteine and 2-oxoglutarate, whereas its two products are S-(4-bromophenyl)mercaptopyruvate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase. Other names in common use include cysteine conjugate aminotransferase, and cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1).