D-aspartate oxidase

Not to be confused with D-amino acid oxidase or Diamine oxidase.

In enzymology, a D-aspartate oxidase (EC 1.4.3.1) is an enzyme that catalyzes the chemical reaction

D-aspartate + H₂O + O₂ ${\displaystyle \rightleftharpoons }$ oxaloacetate + NH₃ + H₂O₂

D-aspartate oxidase
Identifiers
EC no.	1.4.3.1
CAS no.	9029-20-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The 3 substrates of this enzyme are D-aspartate, H₂O, and O₂, whereas its 3 products are oxaloacetate, NH₃, and H₂O₂.

This enzyme belongs to the FAD dependent oxidoreductase family, specifically those acting on the CH-NH₂ group of donors with oxygen as acceptor. The systematic name of this enzyme class is D-aspartate:oxygen oxidoreductase (deaminating). Other names in common use include aspartic oxidase, and D-aspartic oxidase. This enzyme participates in alanine and aspartate metabolism. It employs one cofactor, FAD.

The enzyme is encoded by DDO gene.

See also

• DAO
• Diamine oxidase
• D-amino acid oxidase