D-dopachrome decarboxylase

The enzyme D-dopachrome decarboxylase (EC 4.1.1.84) catalyzes the chemical reaction

D-dopachrome ${\displaystyle \rightleftharpoons }$ 5,6-dihydroxyindole + CO₂

D-dopachrome decarboxylase
Identifiers
EC no.	4.1.1.84
CAS no.	184111-06-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming). Other names in common use include phenylpyruvate tautomerase II, D-tautomerase, D-dopachrome tautomerase, and D-dopachrome carboxy-lyase.