D-methionine—pyruvate transaminase

In enzymology, a D-methionine—pyruvate transaminase (EC 2.6.1.41) is an enzyme that catalyzes the chemical reaction

D-methionine + pyruvate ${\displaystyle \rightleftharpoons }$ 4-methylthio-2-oxobutanoate + L-alanine

D-methionine-pyruvate transaminase
Identifiers
EC no.	2.6.1.41
CAS no.	37277-93-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are D-methionine and pyruvate, whereas its two products are 4-methylthio-2-oxobutanoate and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is D-methionine:pyruvate aminotransferase. Other names in common use include D-methionine transaminase, and D-methionine aminotransferase. This enzyme participates in d-alanine metabolism.