Diaminobutyrate—pyruvate transaminase

In enzymology, a diaminobutyrate-pyruvate transaminase (EC 2.6.1.46) is an enzyme that catalyzes the chemical reaction

L-2,4-diaminobutanoate + pyruvate ${\displaystyle \rightleftharpoons }$ L-aspartate 4-semialdehyde + L-alanine

diaminobutyrate-pyruvate transaminase
Identifiers
EC no.	2.6.1.46
CAS no.	37277-95-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are L-2,4-diaminobutanoate and pyruvate, whereas its two products are L-aspartate 4-semialdehyde and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-2,4-diaminobutanoate:pyruvate aminotransferase. Other names in common use include diaminobutyrate-pyruvate aminotransferase, and L-diaminobutyric acid transaminase. It employs one cofactor, pyridoxal phosphate.