Diguanidinobutanase

In enzymology, a diguanidinobutanase (EC 3.5.3.20) is an enzyme that catalyzes the chemical reaction

1,4-diguanidinobutane + H₂O ${\displaystyle \rightleftharpoons }$ agmatine + urea

diguanidinobutanase
Identifiers
EC no.	3.5.3.20
CAS no.	125268-65-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are 1,4-diguanidinobutane and H₂O, whereas its two products are agmatine and urea.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is 1,4-diguanidinobutane amidinohydrolase.