ELP2

Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene.^[5][6][7]

ELP2
Identifiers
Aliases	ELP2, SHINC-2, STATIP1, StIP, elongator acetyltransferase complex subunit 2, MRT58
External IDs	OMIM: 616054; MGI: 1889642; HomoloGene: 6019; GeneCards: ELP2; OMA:ELP2 - orthologs
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q12.2 Start 36,129,444 bp[1] End 36,180,557 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 A2 Start 24,735,923 bp[2] End 24,772,564 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left ovary Achilles tendon right ovary skin of abdomen ganglionic eminence skin of leg epithelium of colon right uterine tube body of pancreas canal of the cervix Top expressed in saccule otic placode motor neuron facial motor nucleus internal carotid artery condyle external carotid artery primitive streak utricle fossa More reference expression data BioGPS n/a
Gene ontology Molecular function RNA polymerase II complex binding protein kinase binding Cellular component histone acetyltransferase complex transcription elongation factor complex nucleus cytoplasm cytosol elongator holoenzyme complex Biological process regulation of transcription by RNA polymerase II transcription elongation from RNA polymerase II promoter regulation of transcription, DNA-templated transcription, DNA-templated regulation of receptor signaling pathway via JAK-STAT tRNA wobble uridine modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55250 58523 Ensembl ENSG00000134759 ENSMUSG00000024271 UniProt Q6IA86 Q91WG4 RefSeq (mRNA) NM_001242875 NM_001242876 NM_001242877 NM_001242878 NM_001242879 NM_018255 NM_001324465 NM_001324466 NM_001324467 NM_001324468 NM_001324469 NM_021448 NM_001360909 RefSeq (protein) NP_001229804 NP_001229805 NP_001229806 NP_001229807 NP_001229808 NP_001311394 NP_001311395 NP_001311396 NP_001311397 NP_060725 NP_067423 NP_001347838 Location (UCSC) Chr 18: 36.13 – 36.18 Mb Chr 18: 24.74 – 24.77 Mb PubMed search [3] [4]
Wikidata
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Interactions

ELP2 has been shown to interact with STAT3^[6] and Janus kinase 1.^[6]