Erythro-3-hydroxyaspartate ammonia-lyase

The enzyme erythro-3-hydroxyaspartate ammonia-lyase (EC 4.3.1.20) catalyzes the chemical reaction

erythro-3-hydroxy-L-aspartate ${\displaystyle \rightleftharpoons }$ oxaloacetate + NH₃

erythro-3-hydroxyaspartate ammonia-lyase
Identifiers
EC no.	4.3.1.20
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is erythro-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming). Other names in common use include erythro-β-hydroxyaspartate dehydratase, erythro-3-hydroxyaspartate dehydratase, erythro-3-hydroxy-L_s-aspartate hydro-lyase (deaminating); erythro-3-hydroxy-L_s-aspartate ammonia-lyase. It employs one cofactor, pyridoxal phosphate.