Estradiol/norethisterone

Not to be confused with Ethinylestradiol/norethisterone or Estradiol/norethisterone acetate.

Estradiol/norethisterone (E2/NET), tentative brand name Netagen or Netagen 403, was a combination of estradiol (E2), an estrogen, and norethisterone (NET), a progestin, which was studied as a birth control pill to prevent pregnancy in women.^{[1][2][3][4][5]} It was taken by mouth and contained 4 mg micronized E2 and 3 mg NET per tablet.^[2][3] The medication was developed by Novo Pharmaceuticals in Denmark and was never marketed.^[1][2][3]

Estradiol/norethisterone

Estradiol
Norethisterone
Combination of
Estradiol	Estrogen
Norethisterone	Progestogen; Progestin
Clinical data
Other names	E2/NET; Netagen; Netagen 403
Routes of administration	By mouth
Drug class	Estrogen; Progestin; Progestogen
Legal status
Legal status	US: ℞-only
Identifiers
CAS Number	62057-27-6

Two related formulations were Netagen 423 (4 mg estradiol, 2 mg estriol, 3 mg norethisterone) and Netasyn (50 μg ethinylestradiol, 3 mg norethisterone), were also studied but never marketed.^[1][3][4]

See also

• List of combined sex-hormonal preparations § Estrogens and progestogens
• Estradiol-containing birth control pill