Estradiol valerate/megestrol acetate

Estradiol valerate/megestrol acetate (EV/MGA) is a combined injectable contraceptive which was developed in China in the 1980s but was never marketed.^{[1][2][3][4][5]} It is an aqueous suspension of microcapsules (50–80 μm in diameter) containing 5 mg estradiol valerate (EV) and 15 mg megestrol acetate (MGA).^[1][2][4] It was also studied at doses of EV ranging from 0.5 to 5 mg and at doses of MGA ranging from 15 to 25 mg.^[3]

Estradiol valerate /
megestrol acetate

Estradiol valerate (top) and megestrol acetate (bottom)
Combination of
Estradiol valerate	Estrogen
Megestrol acetate	Progestogen
Clinical data
Other names	EV/MGA
Routes of administration	Intramuscular injection (microcapsules)

See also

• List of combined sex-hormonal preparations § Estrogens and progestogens
• Combined injectable birth control § Research