Ethanolamine-phosphate cytidylyltransferase

In enzymology, an ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) is an enzyme that catalyzes the chemical reaction

CTP + ethanolamine phosphate ${\displaystyle \rightleftharpoons }$ diphosphate + CDP-ethanolamine

ethanolamine-phosphate cytidylyltransferase
Identifiers
EC no.	2.7.7.14
CAS no.	9026-33-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are CTP and ethanolamine phosphate, whereas its two products are diphosphate and CDP-ethanolamine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:ethanolamine-phosphate cytidylyltransferase. Other names in common use include phosphorylethanolamine transferase, ET, CTP-phosphoethanolamine cytidylyltransferase, phosphoethanolamine cytidylyltransferase, and ethanolamine phosphate cytidylyltransferase. This enzyme participates in aminophosphonate metabolism and glycerophospholipid metabolism.