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N-Ethylnorketamine

Chemical compound From Wikipedia, the free encyclopedia

N-Ethylnorketamine
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N-Ethylnorketamine (ethketamine, NENK, 2-Cl-2'-Oxo-PCE) is a designer drug which is presumed to have similar properties to ketamine, a dissociative anesthetic drug with hallucinogenic and sedative effects. It has been sold over the internet since around September 2012, and identified in seized drug samples by analytical laboratories in the UK and other European countries.[1]

Quick Facts Clinical data, ATC code ...

It is an NMDA receptor antagonist. In mice its antidepressant effects are dependent on activation of AMPA and 5-HT2 receptors, as blocking those abolishes said activity.[2]

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As of October 2015 NENK is a controlled substance in the United Kingdom,[3] China,[4] and the US state of Alabama.[5]

References

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