FCGR2C

Fc fragment of IgG receptor IIc (gene/pseudogene) is a protein that in humans is encoded by the FCGR2C gene. ^[2]

FCGR2C
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3WJL
Identifiers
Aliases	FCGR2C, CD32, CD32C, CDW32, FCG2, FCRIIC, IGFR2, Fc fragment of IgG receptor IIc (gene/pseudogene), FcgammaRIIc, Fc gamma receptor IIc (gene/pseudogene)
External IDs	OMIM: 612169; GeneCards: FCGR2C; OMA:FCGR2C - orthologs
Gene ontology Molecular function protein binding IgG binding transmembrane signaling receptor activity Cellular component cytoplasm integral component of membrane plasma membrane membrane Biological process immune response signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9103 n/a Ensembl ENSG00000244682 n/a UniProt P31995 n/a RefSeq (mRNA) NM_001005410 NM_001005411 NM_001005412 NM_201563 n/a RefSeq (protein) NP_963857 n/a Location (UCSC) n/a n/a PubMed search [1] n/a
Wikidata
View/Edit Human

Function

This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.