Formylaspartate deformylase

In enzymology, a formylaspartate deformylase (EC 3.5.1.8) is an enzyme that catalyzes the chemical reaction

N-formyl-L-aspartate + H₂O ${\displaystyle \rightleftharpoons }$ formate + L-aspartate

formylaspartate deformylase
Identifiers
EC no.	3.5.1.8
CAS no.	9025-09-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are N-formyl-L-aspartate and H₂O, whereas its two products are formate and L-aspartate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-aspartate amidohydrolase. This enzyme is also called formylaspartic formylase (formylase I, formylase II). This enzyme participates in histidine metabolism and glyoxylate and dicarboxylate metabolism.