Fructose-6-phosphate phosphoketolase

The enzyme fructose-6-phosphate phosphoketolase (EC 4.1.2.22) catalyzes the chemical reaction

D-fructose 6-phosphate + phosphate ${\displaystyle \rightleftharpoons }$ acetyl phosphate + D-erythrose 4-phosphate + H₂O

fructose-6-phosphate phosphoketolase
Identifiers
EC no.	4.1.2.22
CAS no.	37290-57-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming). Other names in common use include D-fructose-6-phosphate D-erythrose-4-phosphate-lyase, and (phosphate-acetylating). This enzyme participates in pentose phosphate pathway.