GTF3C1

General transcription factor 3C polypeptide 1 is a protein that in humans is encoded by the GTF3C1 gene.^[5][6][7]

GTF3C1
Identifiers
Aliases	GTF3C1, TFIIIC, TFIIIC220, TFIIICalpha, general transcription factor IIIC subunit 1
External IDs	OMIM: 603246; MGI: 107887; HomoloGene: 31040; GeneCards: GTF3C1; OMA:GTF3C1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p12.1 Start 27,459,555 bp[1] End 27,549,913 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 F3|7 69.01 cM Start 125,240,126 bp[2] End 125,306,952 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary skin of leg skin of abdomen sural nerve right lobe of thyroid gland ventricular zone left lobe of thyroid gland right hemisphere of cerebellum apex of heart stromal cell of endometrium Top expressed in tail of embryo spermatocyte genital tubercle internal carotid artery external carotid artery dentate gyrus of hippocampal formation granule cell neural layer of retina superior frontal gyrus ventricular zone vestibular membrane of cochlear duct More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding RNA polymerase III general transcription initiation factor activity RNA polymerase III type 1 promoter sequence-specific DNA binding RNA polymerase III type 2 promoter sequence-specific DNA binding Cellular component transcription factor TFIIIC complex nucleolus membrane nucleus nucleoplasm ribonucleoprotein complex Biological process tRNA transcription by RNA polymerase III rRNA transcription tRNA transcription transcription, DNA-templated transcription by RNA polymerase III regulation of transcription by RNA polymerase III transcription initiation from RNA polymerase III promoter 5S class rRNA transcription by RNA polymerase III Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2975 233863 Ensembl ENSG00000077235 ENSMUSG00000032777 UniProt Q12789 Q8K284 RefSeq (mRNA) NM_001286242 NM_001520 NM_207239 RefSeq (protein) NP_001273171 NP_001511 NP_997122 Location (UCSC) Chr 16: 27.46 – 27.55 Mb Chr 7: 125.24 – 125.31 Mb PubMed search [3] [4]
Wikidata
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Interactions

GTF3C1 has been shown to interact with GTF3C4.^[8]