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Geissoschizine dehydrogenase

Class of enzymes From Wikipedia, the free encyclopedia

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In enzymology, a geissoschizine dehydrogenase (EC 1.3.1.36) is an enzyme that catalyzes the chemical reaction

geissoschizine + NADP+ 4,21-didehydrogeissoschizine + NADPH

Thus, the two substrates of this enzyme are geissoschizine and NADP+, whereas its two products are 4,21-didehydrogeissoschizine and NADPH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is geissoschizine:NADP+ 4,21-oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

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