Gentisate decarboxylase

The enzyme gentisate decarboxylase (EC 4.1.1.62) catalyzes the chemical reaction

2,5-dihydroxybenzoate ${\displaystyle \rightleftharpoons }$ hydroquinone + CO₂

gentisate decarboxylase
Identifiers
EC no.	4.1.1.62
CAS no.	37290-54-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming). Other names in common use include 2,5-dihydroxybenzoate decarboxylase, and gentisate carboxy-lyase. This enzyme participates in tyrosine metabolism.