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Gluconate dehydratase

Class of enzymes From Wikipedia, the free encyclopedia

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The enzyme gluconate dehydratase (EC 4.2.1.39) catalyzes the chemical reaction

D-gluconate 2-dehydro-3-deoxy-D-gluconate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include D-gluconate dehydratase, and D-gluconate hydro-lyase. This enzyme participates in the pentose phosphate pathway.

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Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1QJ4.

References

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