Glutamine—scyllo-inositol transaminase

In enzymology, a glutamine-scyllo-inositol transaminase (EC 2.6.1.50) is an enzyme that catalyzes the chemical reaction

L-glutamine + 2,4,6/3,5-pentahydroxycyclohexanone ${\displaystyle \rightleftharpoons }$ 2-oxoglutaramate + 1-amino-1-deoxy-scyllo-inositol

glutamine-scyllo-inositol transaminase
Identifiers
EC no.	2.6.1.50
CAS no.	9033-03-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are L-glutamine and 2,4,6/3,5-pentahydroxycyclohexanone, whereas its two products are 2-oxoglutaramate and 1-amino-1-deoxy-scyllo-inositol.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase. Other names in common use include glutamine scyllo-inosose aminotransferase, L-glutamine-keto-scyllo-inositol aminotransferase, glutamine-scyllo-inosose transaminase, and L-glutamine-scyllo-inosose transaminase. It employs one cofactor, pyridoxal phosphate.