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Glycerol dehydratase

Class of enzymes From Wikipedia, the free encyclopedia

Glycerol dehydratase
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In enzymology, a glycerol dehydratase (EC 4.2.1.30) catalyzes the chemical reaction

glycerol 3-hydroxypropanal + H2O
Thumb
Representation of molecular structure of the protein registered with 1r8w code.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is glycerol hydro-lyase (3-hydroxypropanol-forming). Other names in common use include glycerol dehydrase, and glycerol hydro-lyase. This enzyme participates in glycerolipid metabolism. It employs one cofactor, cobalamin.

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Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1IWP and 1MMF.

References

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