Hydroxyacylglutathione hydrolase

The enzyme hydroxyacylglutathione hydrolase (EC 3.1.2.6, systematic name = S-(2-hydroxyacyl)glutathione hydrolase) catalyzes the following reaction:^[1]

S-(2-hydroxyacyl)glutathione + H₂O = glutathione + a 2-hydroxy carboxylate

Hydroxyacylglutathione hydrolase
Identifiers
EC no.	3.1.2.6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of hydrolases, specifically the class of thioester lyases. It is commonly known as glyoxalase II. It participates in pyruvate metabolism.