Guanosine-diphosphatase

In enzymology, a guanosine-diphosphatase (EC 3.6.1.42) is an enzyme that catalyzes the chemical reaction

GDP + H₂O ${\displaystyle \rightleftharpoons }$ GMP + phosphate

guanosine-diphosphatase
Identifiers
EC no.	3.6.1.42
CAS no.	98037-56-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are GDP and H₂O, whereas its two products are GMP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is GDP phosphohydrolase. This enzyme is also called GDPase.