Influenza A virus subtype H6N2

H6N2 is an avian influenza virus with two forms: one has a low and the other a high pathogenicity. It can cause a serious problem for poultry, and also infects ducks as well.^[1] H6N2 subtype is considered to be a non-pathogenic chicken virus, the host still unknown, but could strain from feral animals, and/or aquatic bird reservoirs.^[2] H6N2 along with H6N6 are viruses that are found to replicate in mice without preadaptation, and some have acquired the ability to bind to human-like receptors.^[3] Genetic markers for H6N2 include 22-amino acid stalk deletion in neuraminidase (NA) protein gene, increased N-glycosylation, and a D144 mutation of the Haemagglutinin (HA) protein gene.^[4] Transmission of avian influenza viruses from wild aquatic birds to domestic birds usually cause subclinical infections, and occasionally, respiratory disease and drops in egg production.^[5] Some histological features presented in chicken infected with H6N2 are fibrinous yolk peritonitis, salpingitis, oophoritis, nephritis, along with swollen kidneys as well.^[6]

Influenza A virus subtype H6N2
Virus classification
(unranked):	Virus
Realm:	Riboviria
Kingdom:	Orthornavirae
Phylum:	Negarnaviricota
Class:	Insthoviricetes
Order:	Articulavirales
Family:	Orthomyxoviridae
Genus:	Alphainfluenzavirus
Species:	Influenza A virus
Serotype:	Influenza A virus subtype H6N2

Signs and symptoms

• sneezing and lacrimation
• prostration
• anorexia and fever
• sometimes swelling of the infraorbital sinuses with nasal mucous ^[7]