Hepatitis C virus cis-acting replication element

The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B. Mutations in this family have been found to cause a blockage in RNA replication and it is thought that both the primary sequence and the structure of this element are crucial for HCV RNA replication.^[1]

Hepatitis C virus (HCV) cis-acting replication element (CRE)
Predicted secondary structure and sequence conservation of HepC_CRE
Identifiers
Symbol	HepC_CRE
Rfam	RF00260
Other data
RNA type	Cis-reg
Domain(s)	Viruses
SO	SO:0000233
PDB structures	PDBe

See also

• Hepatitis C alternative reading frame stem-loop
• Hepatitis C virus 3'X element
• Hepatitis C virus stem-loop VII
• Hepatitis C stem-loop IV
• Hepatitis C