Histidine transaminase

In enzymology, a histidine transaminase (EC 2.6.1.38) is an enzyme that catalyzes the chemical reaction

L-histidine + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ (imidazol-5-yl)pyruvate + L-glutamate

histidine transaminase
Identifiers
EC no.	2.6.1.38
CAS no.	37277-92-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are L-histidine and 2-oxoglutarate, whereas its two products are (imidazol-5-yl)pyruvate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-histidine:2-oxoglutarate aminotransferase. Other names in common use include histidine aminotransferase, and histidine-2-oxoglutarate aminotransferase. This enzyme participates in histidine metabolism.