Hydrogensulfite reductase

In enzymology, a hydrogensulfite reductase (EC 1.8.99.3) is an enzyme that catalyzes the chemical reaction

trithionate + acceptor + 2 H₂O + OH- ${\displaystyle \rightleftharpoons }$ 3 bisulfite + reduced acceptor

hydrogensulfite reductase
Identifiers
EC no.	1.8.99.3
CAS no.	9059-42-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The 4 substrates of this enzyme are trithionate, acceptor, H₂O, and OH-, whereas its two products are bisulfite and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with other acceptors. The systematic name of this enzyme class is trithionate:acceptor oxidoreductase. Other names in common use include bisulfite reductase, dissimilatory sulfite reductase, desulfoviridin, desulforubidin, desulfofuscidin, dissimilatory-type sulfite reductase, and trithionate:(acceptor) oxidoreductase. It has 4 cofactors: iron, sulfur, siroheme, and iron-sulfur.