Indolelactate dehydrogenase

In enzymology, an indolelactate dehydrogenase (EC 1.1.1.110) is an enzyme that catalyzes the chemical reaction

(indol-3-yl)lactate + NAD⁺ ${\displaystyle \rightleftharpoons }$ (indol-3-yl)pyruvate + NADH + H⁺

indolelactate dehydrogenase
Identifiers
EC no.	1.1.1.110
CAS no.	37250-41-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are (indol-3-yl)lactate and NAD⁺, whereas its 3 products are (indol-3-yl)pyruvate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (indol-3-yl)lactate:NAD⁺ oxidoreductase. This enzyme is also called indolelactate:NAD⁺ oxidoreductase. This enzyme participates in tryptophan metabolism.