Isonocardicin synthase

In enzymology, an isonocardicin synthase (EC 2.5.1.38) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + nocardicin E ${\displaystyle \rightleftharpoons }$ 5'-methylthioadenosine + isonocardicin A

isonocardicin synthase
Identifiers
EC no.	2.5.1.38
CAS no.	118246-74-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and nocardicin E, whereas its two products are 5'-methylthioadenosine and isonocardicin A.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase. This enzyme is also called nocardicin aminocarboxypropyltransferase.