Isopenicillin N epimerase

In enzymology, an isopenicillin N epimerase (EC 5.1.1.17) is an enzyme that catalyzes the chemical reaction

isopenicillin N ${\displaystyle \rightleftharpoons }$ penicillin N

isopenicillin N epimerase
Identifiers
EC no.	5.1.1.17
CAS no.	88201-43-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Hence, this enzyme has one substrate, isopenicillin N, and one product, penicillin N.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is penicillin N 5-amino-5-carboxypentanoyl-epimerase. This enzyme participates in penicillin and cephalosporin biosynthesis.