Ketotetrose-phosphate aldolase

The enzyme ketotetrose-phosphate aldolase (EC 4.1.2.2) catalyzes the chemical reaction

erythrulose 1-phosphate ${\displaystyle \rightleftharpoons }$ glycerone phosphate + formaldehyde

ketotetrose-phosphate aldolase
Identifiers
EC no.	4.1.2.2
CAS no.	9024-45-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Hence, this enzyme has one substrate, erythrulose 1-phosphate, and two products, dihydroxyacetone phosphate and formaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include phosphoketotetrose aldolase, erythrulose-1-phosphate synthetase, erythrose-1-phosphate synthase, and erythrulose-1-phosphate formaldehyde-lyase.