Kurzrock–Miller test

The Kurzrock–Miller test is an in-vitro test of sperm–mucus interaction. It consists of establishing an interface between cervical mucus and liquefied semen.^[1] It is one of the tests used for investigating infertility.

Kurzrock–Miller in-vitro slide test of sperm–mucus interaction.

Etymology

The test is named after Raphael Kurzrock and Thomas Grier Miller.^[2]

Interpretation

1. Negative test: Spermatozoa congregate on semen side of the interface, but do not penetrate it.
2. Abnormal: Spermatozoa penetrate the mucus, but rapidly become immobile or acquire shaking movement.
3. Poor: after penetration, spermatozoa do not progress farther than 500 μm.
4. Normal: Spermatozoa penetrate the mucus and >90% are motile with definite progression, crossing 3 cm at 30 minutes.^[3]

See also

• Hamster egg penetration test
• Postcoital test
• Sperm–cervical mucus contact test