L-cysteate sulfo-lyase

The enzyme L-cysteate sulfo-lyase (EC 4.4.1.25) catalyzes the reaction

L-cysteate + H₂O = hydrogensulfite + pyruvate + NH₃ (overall reaction)

(1a) L-cysteate = hydrogensulfite + 2-aminoprop-2-enoate

(1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)

(1c) 2-iminopropanoate + H₂O = pyruvate + NH₃ (spontaneous)

L-cysteate sulfo-lyase
Identifiers
EC no.	4.4.1.25
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteate bisulfite-lyase (deaminating; pyruvate-forming). Other names in common use include L-cysteate sulfo-lyase (deaminating), and CuyA.