L-galactonolactone oxidase

In enzymology, a L-galactonolactone oxidase (EC 1.3.3.12) is an enzyme that catalyzes the chemical reaction

L-galactono-1,4-lactone + O₂ ${\displaystyle \rightleftharpoons }$ L-ascorbate + H₂O₂

L-galactonolactone oxidase
Identifiers
EC no.	1.3.3.12
CAS no.	69403-13-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are L-galactono-1,4-lactone and O₂, whereas its two products are L-ascorbic acid and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donors with oxygen as acceptor. The systematic name of this enzyme class is L-galactono-1,4-lactone:oxygen 3-oxidoreductase. This enzyme is also called L-galactono-1,4-lactone oxidase. This enzyme participates in ascorbic acid and aldaric acid metabolism. It employs one cofactor, FAD.