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L-rhamnose isomerase

From Wikipedia, the free encyclopedia

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In enzymology, a L-rhamnose isomerase (EC 5.3.1.14) is an enzyme that catalyzes the chemical reaction

L-rhamnose L-rhamnulose

Hence, this enzyme has one substrate, L-rhamnose, and one product, L-rhamnulose.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is L-rhamnose aldose-ketose-isomerase. Other names in common use include rhamnose isomerase, and L-rhamnose ketol-isomerase. This enzyme participates in fructose and mannose metabolism.

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Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1D8W, 1DE5, 1DE6, 2HCV, 2I56, and 2I57.

References

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