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LPAR2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

LPAR2
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Lysophosphatidic acid receptor 2 also known as LPA2 is a protein that in humans is encoded by the LPAR2 gene.[5][6][7] LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).[8]

Quick Facts Available structures, PDB ...
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Function

This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.[5]

Interactions

LPAR2 has been shown to interact with TRIP6.[9]

Evolution

Paralogues

Source:[10][11]

See also

References

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Further reading

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