Lactaldehyde reductase (NADPH)

In enzymology, a lactaldehyde reductase (NADPH) (EC 1.1.1.55) is an enzyme that catalyzes the chemical reaction

propane-1,2-diol + NADP⁺ ${\displaystyle \rightleftharpoons }$ L-lactaldehyde + NADPH + H⁺

lactaldehyde reductase (NADPH)
Identifiers
EC no.	1.1.1.55
CAS no.	9028-43-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are 1,2-propanediol and NADP⁺, whereas its 3 products are L-lactaldehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is propane-1,2-diol:NADP⁺ oxidoreductase. Other names in common use include lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate), reductase, NADP⁺-1,2-propanediol dehydrogenase, propanediol dehydrogenase, 1,2-propanediol:NADP⁺ oxidoreductase, and lactaldehyde reductase (NADPH).