Latia-luciferin monooxygenase (demethylating)

In enzymology, a Latia-luciferin monooxygenase (demethylating) (EC 1.14.99.21) is an enzyme that catalyzes the chemical reaction

Latia luciferin + AH₂ + 2 O₂ ${\displaystyle \rightleftharpoons }$ oxidized Latia luciferin + CO₂ + formate + A + H₂O + hnu

Latia-luciferin monooxygenase (demethylating)
Identifiers
EC no.	1.14.99.21
CAS no.	62213-54-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The 3 substrates of this enzyme are Latia luciferin, an electron acceptor AH₂, and O₂, whereas its 6 products are oxidized Latia luciferin, CO₂, formate, the reduction product A, H₂O, and hn.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating). Other names in common use include luciferase (Latia luciferin), and Latia luciferin monooxygenase (demethylating). It has 2 cofactors: FAD, and Flavoprotein.