Leucine N-acetyltransferase

In enzymology, a leucine N-acetyltransferase (EC 2.3.1.66) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-leucine ${\displaystyle \rightleftharpoons }$ CoA + N-acetyl-L-leucine

leucine N-acetyltransferase
Identifiers
EC no.	2.3.1.66
CAS no.	75496-56-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are acetyl-CoA and L-leucine, whereas its two products are CoA and N-acetyl-L-leucine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-leucine N-acetyltransferase. This enzyme is also called leucine acetyltransferase.